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Mifepristone (Mifeprex) and Misoprostol

Mifepristone (mifeprex) and misoprostol is a medical abortion procedure used up to the first 7 to 9 weeks of pregnancy. It is also referred to as RU-486 or the abortion pill.
  • A physical exam is first given in order to determine eligibility for this type of medical abortion procedure. You are not eligible if you have any of the following: ectopic pregnancy, ovarian mass, IUD, corticosteroid use, adrenal failure, anemia, bleeding disorders or use of blood thinners, asthma, liver or kidney problems, heart disease, or high blood pressure. You will be given antibiotics to prevent infection.
  • Mifepristone is given orally during your first office visit. Mifepristone blocks progesterone from the uterine lining, causing the lining to break down, preventing the ability to continue a pregnancy.
  • Misoprostol tablets are taken orally or inserted vaginally about 36 to 72 hours after taking the mifepristone. The tablets will cause contractions and expel the fetus. This process may take a few hours or as long as a few days.
  • A physical exam is given two weeks later to ensure the abortion was complete and to check for complications.

Advantages of medication abortion

The World Health Organization (WHO) believes mifepristone is an important treatment that should be made available to all women. Advantages of taking mifepristone include that:
  • For at least 95 per cent of women up to nine weeks gestation, taking mifepristone with misoprostol results in complete abortion within a few hours.
  • Unlike surgical abortion, medication abortion does not need a surgeon, making it a suitable alternative for women living in remote areas.
  • The risk of maternal death is extremely low.
  • Some women who have used mifepristone have said the procedure is less clinical and stressful than surgical abortion.
  • The abortion happens at home.
  • Anaesthesia is not needed.
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 What is abortion/termination of pregnancy?
Abortion is the ending of pregnancy by removing a fetus or embryo before it can survive outside the uterus. An abortion that occurs spontaneously is also known as a miscarriage. An abortion may be caused purposely and is then called an induced abortion, or less frequently, "induced miscarriage". The word abortion is often used to mean only induced abortions. A similar procedure after the fetus could potentially survive outside the womb is known as a "late termination of pregnancy".
When allowed by law, abortion in the developed world is one of the safest procedures in medicine. Modern methods use medication .The drug mifepristone in combination with prostaglandin appears to be as safe and effective as surgery during the first and second trimester of pregnancy. Birth control, such as the pill , can be used immediately following abortion.When performed legally and safely, induced abortions do not increase the risk of long-term mental or physical problems.
How effective is it?
A Medical Abortion is approximately 95%effective. Mifeprex and Misoprostol will cause serious birth defects to this pregnancy.
Types of Medical Abortion Procedures

The most well-known method of medication abortion uses mifepristone in combination with another drug, misoprostol, to end a pregnancy up to nine weeks. Mifepristone is also known as RU486 or the 'abortion pill'. Medication abortion is a low-risk, non-invasive way to terminate (end) a pregnancy.

Methotrexate & Misoprostol (MTX)

MTX is a medical abortion procedure used up to the first 7 weeks (49 days of pregnancy). This procedure is not as commonly used as in the past because of the availability of mifepristone.
  • Methotrexate is given orally or by injection during the first office visit.
  • Antibiotics are also given in order to prevent infection.
  • Misoprostol tablets are given orally or inserted vaginally about 3 to 7 days later. This can be done at home.
  • This procedure will usually trigger contractions and expel the fetus. The process may take a few hours or as long as a few days.
  • A physical exam is given a week later to ensure that the abortion procedure is complete and to check for complications.
  • Methotrexate is primarily used in the treatment of cancer and rheumatoid arthritis because it attacks the most rapidly growing cells in the body. In the case of abortion, it causes the fetus and placenta to separate from the lining of the uterus. Using the drug for this purpose is not approved by the FDA. 0747095212